Tom Hardy revealed at this years Brazil Comic-Con that his upcoming role as Venom will be based on Venom: Lethal Protector and take place in the arcs setting of San Francisco. The 1993 mini-series was written by David Michelinie with art from Mark Bagley, Sam Delarosa, and Ron Lim. In this arc, Venom and Spider-Man have struck a truce after their long rivalry. Venom moves to San Fransisco to start over but is aggressively pursued by The Life Foundation. Their goals are to study and use the symbiote for their own benefits, thus creating a batch of new symbiotes Phage, Scream, Agony, Lasher, and Riot.
Instead the film will likely use this as a vehicle to bond a symbiote to serial killer Cletus Cassidy, creating Carnage. In the comics the Carnage symbiote is the offspring of the Venom symbiote who bonds with Cassidy after Eddie Brock breaks out of prison. Carnage is one of the most violent villains in all of Marvel Comics even getting his own crossover event, Maximun Carnage. He is considered as Venoms top rival, 2nd to Spider-Man, and as his paternal father Venom feels it’s his charge to bring down the symbiotic psychopath.
Additionally, an animated Spider-Man: Into the Spider-Verse film was announced at the Brazil Comic-Con for December of 2018 which may or may not introduce Miles Morales into Sony’s Spider-Verse. Venom is directed by Ruben Fleischer and hits theatres October 5th, 2018. It will kick off Sony’s Spider-Verse which is set to include Silver & Black, a film based on Silver Sable & Black Cat, and Morbius based on the living Vampire Micheal Mobius.